Pilot Plant Specialist – Oligonucleotides Purification

vor Gesendet 7 Stunden E-Mail Job
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Job Detail

  • Job-ID 331760

Job-Beschreibung

Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.The PositionA healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love.That’s what makes us Roche.In Roche’s ), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.The opportunityWe are seeking a highly skilled and motivated Pilot Plant Specialist in purification to join our team in the downstream processing of oligonucleotides and peptides. The ideal candidate will have extensive experience in GMP and non-GMP environments, with a strong background in preparative chromatography and other downstream processing techniques. Your main tasks and responsibilities will include:Execute downstream processing operations in both GMP and non-GMP settings.Develop preparative chromatographic techniques such as reversed phase and ion exchange and apply these to the purification of Active Pharmaceutical Ingredients (APIs).Document manufacturing processes in accordance with GMP requirements.Coordinate activities related to GMP downstream purification and isolation with other groups such as analytical, warehousing, and quality assurance teams.Maintenance and cleaning of equipment in compliance with GMP standards.Contribute to inventory management and the ordering of materials.Who you areYou thrive in a dynamic, inclusive environment which gives you full accountability for your own contributions and development. You have a keen interest in continuously building a personal network. You are resourceful and flexible in problem solving and in working in a collaborative and inclusive manner. As a purification expert, you will support GMP and non-GMP productions of a variety of oligonucleotide and peptide therapeutics from the Roche portfolio. In addition you bring:Bachelor/Master degree with at least 3 years of experience or Apprenticeship with at least 5 years of experience in the fieldStrong technical expertise and experience in preparative downstream processing of oligonucleotides, peptides, or biologics by using ion exchange and/or reversed phase preparative chromatography systemsExperience in working in a GMP pilot plant environment for low bioburden APIsDigital proficiency and familiarity with software solutions for preparative and analytical chromatography systemsExperience in working in controlled areas (e.g., cleanroom, AtEx) is advantageousKnowledge of SAP or willingness to learn and become acquainted with SAP-based applicationsProficient in both English and GermanOur commitmentRoche commits to recognising talent and aptitude. We prioritise encouraging and supporting our employees on their personal journeys by providing a safe, creative space to help them reflect, make decisions and grow in their career.We are confident that we find the most innovative solutions by gaining different perspectives, asking and answering hard questions, and challenging the status quo. in a serious yet enthusiastic way; we are devoted to building a team that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.Who we areAt Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. .Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.Roche is an Equal Opportunity Employer.

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